Papillex is a nutritional supplement designed to support the immune system using folate, EGCG, zinc, and other active ingredients.
By taking Papillex daily, you can purportedly support your body’s natural defense against HPV and abnormal cervical cells.
Find out everything you need to know about Papillex and how it works today in our review.
What is Papillex?
Papillex is an immune-boosting supplement designed specifically to combat human papillomavirus, or HPV, the most common sexually transmitted infection (STI) in the world.
By taking Papillex daily, you can give your body the nutrients it needs to fight back against HPV.
There is no known cure for HPV. However, supporting your immune system – say, by taking Papillex – can help manage symptoms of the STI.
According to verified reviews on the official website, many people taking Papillex have tested negative for HPV after previously testing positive for the STI. Some have noticed reduced symptoms within weeks of taking Papillex, for example, while others start testing negative after just one or two months.
Papillex is available through Papillex.com, Amazon, and other retailers. It’s priced at around $46 per bottle (60 capsules / 30 servings per bottle).
Papillex Benefits
Some of the benefits of Papillex, according to the manufacturer, include:
- Support your body’s natural defense against HPV
- Targeted nutraceutical support for HPV
- Fight back against symptoms of the world’s most common STI
- Gluten-free, dairy-free, non-GMO, vegan formula
- Made in the United States and exceeding FDA and Health Canada safety standards
- Backed by 60 day money back guarantee
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How Does Papillex Work?
Papillex optimizes your body’s natural immunity, helping it respond to the HPV infection more effectively.
Here’s how the makers of Papillex explain the effects of the supplement:
“By optimizing your natural immunity and replacing missing and low nutrients, Papillex helps you to create an environment inhospitable to HPV.”
To do that, Papillex contains a blend of antioxidant-rich fruits, vegetables, and plant extracts. The supplement contains functional mushrooms, green tea extract, vitamins, minerals, and more.
These ingredients have a similar goal: to make it easier for your immune system to do its job. Some ingredients support healthy inflammation, for example, to help your immune system function better. Other ingredients correct nutritional deficiencies that typically lead to immune dysfunction.
How to Take Papillex
The makers of Papillex recommend taking two capsules once or twice per day (or as directed by your healthcare provider):
- Take 2 capsules of Papillex 1 to 2 times per day
- Take Papillex with or without food
Papillex Ingredients
Papillex contains natural antioxidants, vitamins, minerals, and other nutrients to support your body’s natural defenses against HPV.
Here are all of the active ingredients in Papillex and how those ingredients work:
Broccoli Sprout Extract: Broccoli sprout extract is rich in vitamins, minerals, and nutrients linked to immune function. Some of the most important ingredients in the extract are indole-3-carbinol, DIM, and sulforaphane, all of which can support the body and help repair DNA damage. Instead of eating mountains of broccoli daily, you can take a single serving of Papillex.
Ganoderma Lucidum: Better known as reishi mushroom, Ganoderma lucidum is a functional mushroom used for 2,000+ years in traditional Chinese medicine. According to Papillex.com, “clinical studies have shown that the use of these mushrooms supports the clearance rate of HPV.” The company also claims that use of the mushroom extract “has dramatically impacted the clearance rate of HPV, both vaginal and oral.”
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Lycopene & Carotenoids: Some foods are rich in natural antioxidants like lycopene (found in tomatoes) and carotenoids (found in many vegetables). Studies show people with low lycopene and carotenoid intake tend to have an increased risk of persistent HPV infections. Papillex, Inc. also cites one study showing higher levels of lycopene were associated with decreased risks from HPV.
Vitamin B9: Also known as folate, vitamin B9 is crucial for immune function, and people with folate deficiency tend to have an increased risk of positive HPV and HPV progression. In fact, according to Papillex, Inc., “Folate is important in regulating HPV” overall.
Vitamin C: Vitamin C is one of the best antioxidants in the natural world, and many people take vitamin C supplements at the onset of illness. Vitamin C, like other antioxidants, can neutralize free radicals and support your body’s immune function, helping you defend your body against foreign pathogens. According to Papillex, Inc. “individuals with higher vitamin C levels better regulate HPV viral load.”
Zinc: Zinc, like vitamin C, is commonly taken at the onset of illness to speed up the body’s recovery. Studies show people with zinc deficiency tend to have worse immune systems than people who get their daily recommended dose of zinc.
Green Tea Extract: Papillex contains camelia sinensis or green tea extract. Considered one of the healthiest beverages in the world, green tea is packed with natural antioxidants linked to weight loss, healthy inflammation, and other benefits. Green tea is particularly rich wi catechins like EGCG, which appear to be particularly helpful for boosting immunity. According to the makers of Papillex, green tea intake “has been associated with slowed progression of abnormal cells through its powerful antioxidant effects.”
Vitamin E: Vitamin E has similar benefits to vitamin C: it’s a natural antioxidant linked to positive effects on inflammation and immune function. Papillex, Inc. cites one clinical study showing vitamin E “has been shown…to inhibit abnormal cervical cell growth” while supporting overall immune function.
Selenium: A trace mineral, selenium is found in certain foods – like nuts – and is crucial for processes throughout the body. According to Papillex, Inc., people with cervical dysplasia may have “deficient levels of selenium.” Taking a selenium supplement could help promote overall immune function.
Astragalus: The final ingredient in Papillex is astragalus, an adaptogenic plant extract used for centuries in Ayurvedic medicine. Astragalus can help the body respond to stressors while promoting overall resilience. Some studies specifically connect the plant extract to regular cervical cell function. According to Papillex, Inc., the herb can impact the “growth of dysregulated cervical epithelial cells,” helping to regulate the growth of these cells and reduce their expression.
Overall, Papillex, Inc. emphasizes using natural, science-backed ingredients to fight against HPV and boost the immune system.
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What to Expect After Taking Papillex
Some of the results you could experience after taking Papillex, according to the manufacturer, include:
Help the Body Respond to the HPV Virus: The primary goal of Papillex is to help the body respond to HPV. When your body is infected with HPV, it sends your immune system into action. Your immune system needs a lot of help defending against HPV. Papillex, Inc. says the supplement “enables it [the body] to effectively respond to the HPV virus, regulating it as a part of the human microbiome.”
Restore Healthy Immune Response: Many of the ingredients in Papillex are designed to support healthy immune response and function overall. For example, vitamin C, zinc, and selenium are commonly found in immune booster supplements. You might take these ingredients at the onset of cold and flu symptoms to speed up your body’s recovery. Those properties make these ingredients effective for restoring healthy immune responses in people with HPV.
Support Healthy Inflammation for Better Immune Function: Your body uses inflammation to fight against disease and infections. Too much inflammation, however, can lead to chronic illness and pain. It’s a sign your body’s immune system isn’t working as it should. Papillex supports healthy inflammation using natural antioxidants like vitamins C and E.
Correct Nutritional Deficiencies: People with HPV are more likely to be deficient in certain nutrients than people without HPV. Papillex works by correcting these nutritional deficiencies, helping you restore optimal immune function. If you have HPV and ignore these deficiencies, then you could struggle to fight back against the STI.
Restore Your Body Overall: Many Papillex ingredients are designed to restore your body. They can promote immune function, support DNA repair, and assist your body in repairing itself from an HPV infection.
Promote Normal Immune Function without Medically Treating HPV: The goal of Papillex is not to medically treat an HPV infection; instead, it’s about supporting normal immune system function in the presence of HPV. The supplement isn’t designed to attack HPV directly; it supports your immune system to help promote your body’s natural defenses against HPV.
Does Not Cure HPV: Papillex, Inc. is careful to remind users there is “no cure for HPV.” However, supporting the immune system using Papillex can “help to manage symptoms when the infection is active.” And, according to reviews from verified purchasers shared on the official website, many customers have tested negative for HPV after using Papillex.
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Scientific Evidence for Papillex
Can a nutritional supplement help defend against the symptoms of HPV? How does Papillex help some people test negative for HPV after a positive test? We’ll review the science behind Papillex and how it works below.
The largest ingredient in Papillex is green tea extract. Green tea extract has been standardized to contain many natural antioxidants, including polyphenols and catechins like EGCG. Some studies have shown green tea extract can specifically help with HPV-related cervical disease.
In a 2003 study, for example, researchers found oral green tea supplementation helped improve cervical lesions over an 8 to 12-week period. A separate study found that taking 800mg of EGCG daily for four months significantly improved HPV clearance. Finally, a 2020 study showed catechins in green tea could help with viral warts and HPV-related and unrelated cancers. Overall, green tea is one of the most science-backed natural ingredients for defending your body against HPV, with multiple trials validating its effects.
Broccoli, the second largest ingredient in Papillex, has also been shown to impact cervical cancer cells positively. In a 2016 study, researchers found sulforaphane, a natural molecule within broccoli, positively impacted cervical cancer cells by downregulating the expression of certain genes and upregulating certain proteins. The broccoli extract in Papillex has also been specifically designed to optimize levels of sulforaphane.
Reishi mushroom has been used for centuries in traditional Chinese medicine and is validated by multiple modern trials. A 2014 study, for example, found Ganoderma lucidum (reishi) could boost the clearance of HPV over 1 to 2 months.
Papillex also contains a group of vitamins and minerals linked to hundreds of processes throughout the body. One study found zinc, selenium, vitamin C, vitamin E, and other micronutrients in Papillex appeared to play a role in HPV, although more research is needed to verify this connection.
The remaining ingredients in Papillex have also been connected to HPV in some studies. Astragalus, for example, was shown to improve cervical cancer outcomes when used as a complement to chemotherapy, according to a 2021 review and meta-analysis. Lycopene and carotenoids, meanwhile, were shown to help fight back against persistent HPV, decreasing tested levels of HPV in a group of Brazilian women, according to a study published in 2012.
Overall, Papillex contains a science-backed blend of ingredients shown to support your body’s natural clearance of HPV, and most ingredients are backed by formal clinical trials proving they work as advertised.
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Papillex Supplement Facts Label
The makers of Papillex disclose all ingredients in the formula upfront, including the specific dosages of each ingredient and all inactive ingredients used to hold the formula together.
Here’s what you get in each two-capsule serving of Papillex:
- 250mg of green tea leaf extract (decaffeinated and standardized to contain 80% catechins, 50% EGCG, and 98% polyphenols)
- 200mg of broccoli sprout powder (in the form of HiActives)
- 100mg of astragalus root extract (5:1 extract, equivalent to 500mg of fresh astragalus)
- 70mg of natural lycopene extract (with 5% lycopene)
- 50mg of reishi mushroom extract (8:1 extract, equivalent to 400mg of fresh reishi)
- 900mcg RAE of vitamin A (100% DV)
- 90mg of vitamin C (100% DV)
- 40mg AT of vitamin E (268% DV)
- 800mcg DFE of folate (200% DV)
- 2.4mcg of vitamin B12 (100% DV)
- 11mg of zinc (100% DV)
- 55mcg of selenium (100% DV)
Other (inactive) ingredients, including hypromellose (to create the capsule), rice flour, and magnesium stearate
Other Papillex Features
Why pick Papillex? What else makes the supplement unique?
Here are some of the features that distinguish Papillex from other HPV supplements and immune-boosting formulas available today:
Specifically for HPV: Papillex is designed specifically to boost your immune system’s natural defenses against the world’s most common STI: HPV. You can find other supplements that boost your immunity and support immune function overall, but Papillex is one of the few designed specifically for HPV.
Proactive Defense Against HPV Instead of a “Wait & See” Approach: Many doctors advocate a “watch and wait” or “wait and see” approach to HPV. You might have had an abnormal pap smear, so your doctor recommends paying attention to the issue until your next pap smear. Papillex, Inc. believes in a different approach, being proactive against HPV. HPV diagnoses can be frightening, and HPV rates are rising. Papillex was specifically designed as a natural way to fight back against HPV.
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Doctor-Endorsed: The official Papillex.com website has an endorsement from at least one doctor. Dr. Connors has publicly endorsed Papillex and claims to have “used Papillex in my clinic for a decade with great results.” Prior to the invention of Papillex, she used to recommend “10 different products at a high cost” to her patients. With Papillex, patients can buy a single supplement instead of 10 separate supplements.
Formulated by a Naturopathic Doctor: Papillex was formulated by a naturopathic doctor (ND), and the supplement has been a leading HPV formula since its launch in 2008. Dr. Elizabeth Goldspink, founder and owner of Papillex, Inc., created the formula to help a friend deal with the condition.
Made in North America: Papillex is made in North America to standards that exceed those set by the FDA and Health Canada.
Free of Many Common Allergens & Additives: Papillex is non-GMO, gluten-free, dairy-free, nut-free, vegan, and filler-free.
Pure, cGMP-Certified Suppliers: Papillex, Inc. uses pure ingredients sourced specifically from cGMP-certified suppliers.
Papillex Reviews: What Do Customers Say?
Papillex has hundreds of reviews from verified purchasers online, including users on Amazon, the official Papillex.com online store, and other sources who have used Papillex and noticed positive results.
Here are some of the Papillex reviews shared by verified purchasers across the internet:
One customer tested positive for 2 high-risk strains of HPV for 9 consecutive years. She thought her body would never clear the virus. After taking Papillex and 500mg of AHCC for three months, however, she tested HPV negative on her latest pap smear.
Other customers have noticed similar results, testing negative for HPV after previously testing positive. One customer claims she tested positive for low-risk HPV, then took an entire bottle of Papillex over a month and re-tested, only to find “the HPV was completely gone.”
On the official Papillex.com website, the supplement has an average rating of 4.8 stars out of 5 with 140+ reviews, with all customers giving it a 4-star (19 reviewers) or 5-star (122 reviews) rating. Overall, most verified purchasers are happy with Papillex and how it works.
Many customers notice significant results within weeks of taking Papillex. One customer claims she “saw my HPV clearing up” after taking Papillex for just two weeks, for example. After taking it for 90 days, she noticed even better results. She noticed one wart pop up after 30 days but has noticed nothing since then. Overall, she is “impressed by the results from” Papillex.
Medical practitioner Dr. Connors has publicly endorsed Papillex on Papillex.com, claiming to have used the supplement in the clinic for the last decade with “great results.” Instead of telling her patients to take 10 different supplements, she can tell them to take Papillex.
Papillex has an average rating of 4.3 stars out of 5 on Amazon from 620+ verified purchasers. The vast majority (71%) of reviewers gave the supplement a perfect 5-star rating.
Many Amazon customers praise Papillex for helping their body clear HPV naturally, finding they tested negative after taking Papillex.
Overall, Papillex has existed since 2008 and has helped thousands of women manage symptoms of HPV. The internet is filled with reviews from customers who have experienced powerful effects after taking Papillex.
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Papillex Pricing
Papillex is priced at $45.95 per bottle. The more bottles you buy, the more you can save.
- 1 Bottle: $45.95
- 3 Bottles: $123.95 ($41.32 Per Bottle)
- 6 Bottles: $227.95 ($37.99 Per Bottle)
Each bottle of Papillex contains a 30-day supply or 60 capsules (30 servings). You take two capsules once or twice daily to help support your immune system against HPV.
You can buy Papillex online through the official website Papillex.com.
Papillex Refund Policy
Papillex has a 30-day refund policy. You have 30 days to request a refund, although this policy only applies to unopened products in their original packaging. If you have already opened Papillex and were unhappy with the results of the supplement, then you cannot obtain a refund on that opened bottle.
- Returns Address: 3100 Technology Drive, Plano, TX 75074
Other Papillex, Inc. Supplements
Papillex is best known for its flagship supplement, Papillex. However, the company also offers two other supplements to target other STIs, including AHCC (to defend the body against colds, flu, herpes (HSV), and HPV) and Simplix (designed specifically for herpes simplex virus or HSV and cold sores).
Here are both other Papillex, Inc. supplements and how they work:
AHCC
In addition to Papillex, AHCC is one of the internet’s best-known HPV and immune support supplements.
Backed by 30 human clinical studies, AHCC features shiitake mushrooms to strengthen the immune system to protect against colds and flu while promoting overall well-being.
Some of the benefits of AHCC, according to Papillex, include:
- Support the immune system
- Improve the body’s response to infection
- Backed by 30 clinical trials, including 20 human trials
The supplement delivers a blend of polysaccharides, including alpha and beta-glucans. Polysaccharides are naturally found in plants and have been shown to promote immune function, healthy inflammation, and overall health and wellness, among other benefits.
Simplix
Simplix is the third immune support supplement from Papillex, Inc. Unlike the previous two HPV supplements; however, Simplix is designed specifically for the herpes simplex virus (HSV).
Simplix uses a blend of natural ingredients to enhance your immunity, helping your body defend itself against the virus and support relief from herpes symptoms.
The formula contains a blend of natural ingredients found in medicinal mushrooms and wild seaweeds. Each capsule contains Andrographis, licorice root, lemon balm, vitamin B12, vitamin C, zinc, and L-lysine to promote immune function.
Some of the benefits of Simplix, according to Papillex, include:
- Target the herpes simplex virus (HSV)
- Support your immune system
- Reduce stress
- Replenish essential nutrients
Overall, Simplix is designed to combine the best immune-boosting ingredients from land and sea into one convenient formula, helping to create a shield against the herpes simplex virus and other challenges to your immune system.
About Papillex, Inc.
Papillex is made in the United States by a Texas-based company named Papillex, Inc.
The company was founded in 2008 after the creator of Papillex, a naturopathic doctor (ND), helped a friend regulate abnormal cervical cell changes on a pap spear. That naturopathic doctor found the cells responded to certain natural ingredients, leading to the development of Papillex.
You can contact Papillex, Inc. and the company’s customer service team via the following:
- Email: customerservice@papillex.com
- Online Form: https://papillex.com/contact/
- Phone: (917) 383-0672
- Mailing Address: 3100 Technology Drive, Plano, TX 75074
Papillex, Inc. is led by Dr. Elizabeth Goldspink, ND (Founder and Owner). The company also relies on the expertise of Dr. Jenny Henderson, ND, as its Chief Science Officer.
In addition to Papillex, the company is known for AHCC and Simplix, two other supplements to defend the body against common STIs.
Final Word
Papillex is one of the world’s best-known HPV supplements.
Using natural ingredients, the supplement boosts the immune system by blending plant extracts, mushroom extracts, vitamins, and minerals, helping your body defend itself against HPV.
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